Endocrine Abstracts

Background: Thyroid cancer incidence is increasing, especially the cancers ≤1 cm (T1a). Previous evidence suggests underuse of FNA. Several international guidelines for the management of thyroid cancer have been published. Especially the year 2006 was a hallmark, with the publication of both the ETA consensus and ATA guidelines.Aim: Compare thyroid cancer subtypes and management before and after 2006.Methodology: Retrospectiv...

Background and objective: Increased prescription of levothyroxine (LT4) has been observed in the USA and countries in Europe and has been related to increased thyroid function screening and a lower treatment threshold, increasing risk for overdiagnosis and overtreatment. We wanted to study the evolution of LT4 prescriptions in Belgium, and compare the use of anti-arrhythmic drugs (AAD) and bone-anti-resorptive drugs (BAD) between LT4-users and non-LT4-users.<p class="abste...

Introduction: Several studies identified pre-treatment parameters that could help in the prediction of the thyroid functional outcome after radioactive iodine therapy (RAI) in Graves’ disease. However, the role of the thyroid peroxidase antibody (TPO Ab) status is not well studied.Objectives: We investigated if a positive TPO Ab status before radioactive iodine (RAI) therapy in patients with Graves’ hyperthyroidism is a predictive factor for de...

Inroduction: Primary hyperparathyroidism most commonly presents with hypercalcemia. Rarely, parathyroid apoplexy or haemorrhage, mimicking a thyroid bleeding cyst is the first presentation of a parathyroid adenoma(1,3).Case Report: A 55-year-old woman presented to the ENT department with a sudden onset painful goiter. Ultrasound revealed a sharply defined hypoechogenic nodule in the right thyroid lobe measuring 24.1 x 17.8 x 18.2 mm. The patie...

Objective: We investigated if a positive thyroid peroxidase antibody (TPO Ab) status before radioactive iodine (RAI) therapy in patients with Graves’ hyperthyroidism is a predictive factor for developing hypothyroidism after RAI.Methods: We performed a retrospective study of patients with Graves’ hyperthyroidism with known TPO Ab status, receiving a first administration of RAI. Patients from 4 thyroid outpatient centres in Belgium receiving a f...

Aim: To determine the association between thyroid function and the risk for gestational diabetes mellitus (GDM) and adverse pregnancy outcomes.Methods: This case-control study was a sub-analysis of the BEDIP-N study, in which 199 GDM women were matched for age and body mass index with 398 controls. Thyroid stimulating hormone (TSH), free thyroxine (fT4), free triiodothyronine (fT3), and thyroid peroxidase (TPO) antibodies were measured at 6-14 weeks and ...